CD79B (also known as B29, Ig beta and B cell antigen receptor complex-associated protein beta-chain) is a 36-40 kDa member of the Ig-Superfamily. It is expressed on B cells, and forms a covalent heterodimer with CD79A. This complex interacts non-covalently with membrane Ig, forming the B cell antigen receptor. Within this complex, membrane Ig detects antigen while CD79AB initiates signaling. Mature human CD79B is a 201 amino acid (aa) type I transmembrane glycoprotein (aa 29 229). It contains an extracellular region with one V-type Ig-like domain (aa 38-138) and an ITAM-containing cytoplasmic domain (aa 185-213). There is an alternative splice form that shows a deletion of aa 41-144 and appears after B cell activation. Human CD79A and B share only 26% aa identity. Over aa 29-159, human CD79B shares 54% aa identity with mouse CD79B.
高纯度、高活性、低内毒素、高批间一致性
产品数据
Tris-Bis PAGE
Human CD79B on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
SEC-HPLC
The purity of Human CD79B is greater than 95% as determined by SEC-HPLC.
ELISA Data
Immobilized Human CD79B, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Anti-CD79B Antibody, hFc Tag with the EC50 of 1.8ng/ml determined by ELISA.
-25 ~ -15℃保存，收到货之后有效期1年。
复溶后， 无菌条件下，-85 ~ -65℃保存，3个月有效期。
