This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
推荐稀释比 FC:1/50-1/100;ELISA:1/10000
Flow Cytometry analysis of HL-60 cells using FCAR antibody (green) and negative control (red).
-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。
